Heart Disease, Palliative Care, Hospital Readmissions
January 23, 2020

Hospitalizations and Procedures Remain Common Among Advanced HF Patients, but Hospice and Palliative Care Can Help

"Healthcare utilization peaks at the end of life (EOL) in patients with heart failure (HF)," state the authors of a study published in Circulation: Heart Failure, noting that this trend continues in spite of research showing that aggressive care and hospital deaths often conflict with patients' and caregivers' EOL goals.

Although the study authors are optimistic—noting that both hospice and palliative care (PC) use increased among patients in their cohort through the years of the study—they advocate for increased awareness of risk factors affecting HF patient hospitalizations near death, and for increased hospice and PC referrals for HF patients.

“These data…highlight the need for EOL care pathways that encompass patients with a high comorbidity burden. Care directed only at a patient’s HF may not decrease (healthcare) utilization.”Shannon M. Dunlay, MD, MS, Mayo Clinic

HF incidence in U.S. patients is expected to continue to rise, the authors state, and they describe the resulting EOL healthcare as a "tremendous burden... on patients, caregivers and the healthcare system." Research into HF care trends and risk factors for hospitalization and other procedures near the EOL is necessary for reducing this burden and improving EOL care of HF patients, they point out.

Researchers conducted a longitudinal cohort study of adults with heart failure living in Southeastern Minnesota. The cohort included patients enrolled between 2003 and 2011 who died during the study period, which lasted through the end of 2012. Various health and demographic data were collected, including ejection fraction (EF), Charlson Comorbidity Index, marital status, and use of skilled nursing facility (SNF), hospice and PC.

Overall Findings

Among the 698 HF patients included in the study (47.3% men; mean age at death, 82 years):

  • 81.5% were hospitalized at least once during the last year of life, with a median of two hospitalizations per person (range, 0-12); 28.4% died in the hospital.
  • There was a median of 14 outpatient visits per person (range, 0-119) at the EOL.
  • 50.7% were cared for in a SNF at the EOL.
  • 35.4% received hospice care.
  • 26.5% received a PC consultation.
  • The most common causes of hospitalization were HF (22.1% of hospitalizations), pneumonia (5.2%), sepsis (4.3%) and arrhythmia (3.8%).

Risk Factors and Associations

Older patients were less likely to be hospitalized (for patients ≥ 90 years vs < 75 years: incidence rate ratio [IRR], 0.52; 95% confidence interval [CI], 0.41-0.65) or have outpatient visits in the final year of life.

Factors associated with higher EOL healthcare utilization included living in a SNF (IRR for hospitalizations, 1.35; 95% CI, 1.16-1.58; IRR for outpatient procedures, 1.48; 95% CI, 1.29-1.70) and being married or living with a partner (hospitalization IRR, 1.20; 95% CI, 1.02-1.42; outpatient IRR, 1.22; 95% CI, 1.05-1.41).

Number of comorbidities was associated with number of hospitalizations (for Charlson Comorbidity Index > 6 vs 0-2: hospitalization IRR, 1.71; 95% CI, 1.36-2.14) but not outpatient visits.

Hospice and PC Trends Over Time

During the study period, the rate of hospice use increased (2003-2006: 28.6%; 2007-2009: 34.2%; 2010-2012: 42.2%). Likewise, the number of patients receiving PC consultations increased from 10.8% from 2003-2006 to 43.6% from 2010-2012.

Resource: Hospice Admission Guidelines for Heart Disease

In addition, there was "a dramatic decline in healthcare utilization at the EOL over time, concordant with increases in palliative care consultations and hospice enrollment," the authors write. From the earliest to latest study years, hospital deaths decreased significantly (2003-2006: 32.8%; 2007-2009: 30.6%; 2010-2012: 22.4%), hospitalizations decreased by 46%, and outpatient visits decreased by 32%.

The researchers note that the dramatic increase seen in PC consultations from 2003-2012 "may reflect increased recognition by clinicians of the importance of palliative care in patients with HF approaching the EOL."

Although the authors acknowledge positive changes have occurred in HF EOL care, they stress that their findings underscore that EOL healthcare use in certain subgroups, especially those with multimorbidity, remains high. "[C]are pathways that are not HF specific, but rather encompass the growing population of patients with multimorbidity, need to be developed," they write.

Source: Dunlay, S. M., Redfield, M. M., Jiang, R., Weston, S. A., & Roger, V. L. (2015). Care in the last year of life for community patients with heart failure. Division of Cardiovascular Diseases, Dept. of Medicine, Mayo Clinic. Circulation: Heart Failure, 8(3), 489-496.

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